Bio-Techne (TECH)

Underperform
We wouldn’t buy Bio-Techne. Its weak sales growth and declining returns on capital show its demand and profits are shrinking. StockStory Analyst Team
Anthony Lee, Lead Equity Analyst
Kayode Omotosho, Equity Analyst

2. Summary

Underperform

Why We Think Bio-Techne Will Underperform

With a catalog of hundreds of thousands of specialized biological products used in laboratories worldwide, Bio-Techne (NASDAQ:TECH) develops and manufactures specialized reagents, instruments, and services that help researchers study biological processes and enable diagnostic testing and cell therapy development.

  • Revenue base of $1.22 billion puts it at a disadvantage compared to larger competitors exhibiting economies of scale
  • Sales trends were unexciting over the last two years as its 3.1% annual growth was below the typical healthcare company
  • Anticipated sales growth of 1.8% for the next year implies demand will be shaky
Bio-Techne doesn’t check our boxes. We’d search for superior opportunities elsewhere.
StockStory Analyst Team

Why There Are Better Opportunities Than Bio-Techne

Bio-Techne’s stock price of $64.61 implies a valuation ratio of 32.3x forward P/E. Not only is Bio-Techne’s multiple richer than most healthcare peers, but it’s also expensive for its fundamentals.

There are stocks out there similarly priced with better business quality. We prefer owning these.

3. Bio-Techne (TECH) Research Report: Q4 CY2025 Update

Life sciences company Bio-Techne (NASDAQ:TECH) reported Q4 CY2025 results topping the market’s revenue expectations, but sales were flat year on year at $295.9 million. Its non-GAAP profit of $0.46 per share was 5.8% above analysts’ consensus estimates.

Bio-Techne (TECH) Q4 CY2025 Highlights:

  • Revenue: $295.9 million vs analyst estimates of $290.2 million (flat year on year, 2% beat)
  • Adjusted EPS: $0.46 vs analyst estimates of $0.43 (5.8% beat)
  • Adjusted EBITDA: $103.4 million vs analyst estimates of $95.36 million (35% margin, 8.4% beat)
  • Operating Margin: 18.4%, up from 16% in the same quarter last year
  • Free Cash Flow Margin: 25.9%, similar to the same quarter last year
  • Organic Revenue was flat year on year (beat)
  • Market Capitalization: $10.07 billion

Company Overview

With a catalog of hundreds of thousands of specialized biological products used in laboratories worldwide, Bio-Techne (NASDAQ:TECH) develops and manufactures specialized reagents, instruments, and services that help researchers study biological processes and enable diagnostic testing and cell therapy development.

Bio-Techne operates through two main segments: Protein Sciences (about 72% of sales) and Diagnostics & Genomics. The Protein Sciences segment provides critical biological components like cytokines, growth factors, antibodies, and small molecules that researchers use to investigate cellular functions and disease mechanisms. These products serve as essential tools for scientists trying to understand complex biological pathways or develop new therapeutic approaches.

The company's analytical instruments help researchers quantify and analyze proteins in biological samples. For example, a pharmaceutical company developing a cancer treatment might use Bio-Techne's automated western blotting systems to measure how their experimental drug affects specific protein levels in tumor cells.

In the Diagnostics & Genomics segment, Bio-Techne offers spatial biology tools that allow researchers to visualize gene expression within intact tissue samples, preserving the crucial spatial context of cellular interactions. The segment also includes molecular diagnostic tests like the ExoDx Prostate test, which helps physicians determine if a prostate biopsy is necessary by analyzing exosomes (tiny vesicles) in urine samples.

Bio-Techne sells directly to researchers in academic institutions, pharmaceutical companies, biotechnology firms, and contract research organizations. The company also supplies diagnostic reagents to instrument manufacturers on an OEM basis, providing the calibrators and controls needed for clinical diagnostic tests.

The cell and gene therapy market represents a significant growth opportunity for Bio-Techne. The company has invested heavily in facilities to produce GMP-grade (Good Manufacturing Practice) proteins and reagents required for therapeutic applications. These specialized materials must meet strict quality standards as they're used in the development and production of advanced therapies that modify a patient's cells to treat diseases.

4. Research Tools & Consumables

The life sciences subsector specializing in research tools and consumables enables scientific discoveries across academia, biotechnology, and pharmaceuticals. These firms supply a wide range of essential laboratory products, ensuring a recurring revenue stream through repeat purchases and replenishment. Their business models benefit from strong customer loyalty, a diversified product portfolio, and exposure to both the research and clinical markets. However, challenges include high R&D investment to maintain technological leadership, pricing pressures from budget-conscious institutions, and vulnerability to fluctuations in research funding cycles. Looking ahead, this subsector stands to benefit from tailwinds such as growing demand for tools supporting emerging fields like synthetic biology and personalized medicine. There is also a rise in automation and AI-driven solutions in laboratories that could create new opportunities to sell tools and consumables. Nevertheless, headwinds exist. These companies tend to be at the mercy of supply chain disruptions and sensitivity to macroeconomic conditions that impact funding for research initiatives.

Bio-Techne competes with several life sciences tools providers including Thermo Fisher Scientific (NYSE:TMO), Danaher (NYSE:DHR), Agilent Technologies (NYSE:A), and Abcam (NASDAQ:ABCM). In the spatial biology and diagnostics space, competitors include 10x Genomics (NASDAQ:TXG) and NeoGenomics (NASDAQ:NEO).

5. Revenue Scale

Larger companies benefit from economies of scale, where fixed costs like infrastructure, technology, and administration are spread over a higher volume of goods or services, reducing the cost per unit. Scale can also lead to bargaining power with suppliers, greater brand recognition, and more investment firepower. A virtuous cycle can ensue if a scaled company plays its cards right.

With just $1.22 billion in revenue over the past 12 months, Bio-Techne is a small company in an industry where scale matters. This makes it difficult to build trust with customers because healthcare is heavily regulated, complex, and resource-intensive.

6. Revenue Growth

A company’s long-term sales performance is one signal of its overall quality. Any business can put up a good quarter or two, but the best consistently grow over the long haul. Thankfully, Bio-Techne’s 8.8% annualized revenue growth over the last five years was decent. Its growth was slightly above the average healthcare company and shows its offerings resonate with customers.

Bio-Techne Quarterly Revenue

Long-term growth is the most important, but within healthcare, a half-decade historical view may miss new innovations or demand cycles. Bio-Techne’s recent performance shows its demand has slowed as its annualized revenue growth of 3% over the last two years was below its five-year trend. Bio-Techne Year-On-Year Revenue Growth

We can dig further into the company’s sales dynamics by analyzing its organic revenue, which strips out one-time events like acquisitions and currency fluctuations that don’t accurately reflect its fundamentals. Over the last two years, Bio-Techne’s organic revenue averaged 3% year-on-year growth. Because this number aligns with its two-year revenue growth, we can see the company’s core operations (not acquisitions and divestitures) drove most of its results. Bio-Techne Organic Revenue Growth

This quarter, Bio-Techne’s $295.9 million of revenue was flat year on year but beat Wall Street’s estimates by 2%.

Looking ahead, sell-side analysts expect revenue to grow 3.6% over the next 12 months, similar to its two-year rate. This projection is underwhelming and suggests its newer products and services will not catalyze better top-line performance yet.

7. Operating Margin

Operating margin is an important measure of profitability as it shows the portion of revenue left after accounting for all core expenses – everything from the cost of goods sold to advertising and wages. It’s also useful for comparing profitability across companies with different levels of debt and tax rates because it excludes interest and taxes.

Bio-Techne has been an efficient company over the last five years. It was one of the more profitable businesses in the healthcare sector, boasting an average operating margin of 20%.

Analyzing the trend in its profitability, Bio-Techne’s operating margin decreased by 15.9 percentage points over the last five years. The company’s two-year trajectory also shows it failed to get its profitability back to the peak as its margin fell by 13.8 percentage points. This performance was poor no matter how you look at it - it shows its expenses were rising and it couldn’t pass those costs onto its customers.

Bio-Techne Trailing 12-Month Operating Margin (GAAP)

This quarter, Bio-Techne generated an operating margin profit margin of 18.4%, up 2.4 percentage points year on year. This increase was a welcome development and shows it was more efficient.

8. Earnings Per Share

Revenue trends explain a company’s historical growth, but the long-term change in earnings per share (EPS) points to the profitability of that growth – for example, a company could inflate its sales through excessive spending on advertising and promotions.

Bio-Techne’s solid 7.7% annual EPS growth over the last five years aligns with its revenue performance. This tells us it maintained its per-share profitability as it expanded.

Bio-Techne Trailing 12-Month EPS (Non-GAAP)

In Q4, Bio-Techne reported adjusted EPS of $0.46, up from $0.42 in the same quarter last year. This print beat analysts’ estimates by 5.8%. Over the next 12 months, Wall Street expects Bio-Techne’s full-year EPS of $1.97 to grow 5.7%.

9. Cash Is King

Although earnings are undoubtedly valuable for assessing company performance, we believe cash is king because you can’t use accounting profits to pay the bills.

Bio-Techne has shown robust cash profitability, giving it an edge over its competitors and the ability to reinvest or return capital to investors. The company’s free cash flow margin averaged 22.1% over the last five years, quite impressive for a healthcare business.

Taking a step back, we can see that Bio-Techne’s margin dropped by 11.6 percentage points during that time. Continued declines could signal it is in the middle of an investment cycle.

Bio-Techne Trailing 12-Month Free Cash Flow Margin

Bio-Techne’s free cash flow clocked in at $76.49 million in Q4, equivalent to a 25.9% margin. This cash profitability was in line with the comparable period last year and above its five-year average.

10. Return on Invested Capital (ROIC)

EPS and free cash flow tell us whether a company was profitable while growing its revenue. But was it capital-efficient? Enter ROIC, a metric showing how much operating profit a company generates relative to the money it has raised (debt and equity).

Bio-Techne’s management team makes decent investment decisions and generates value for shareholders. Its five-year average ROIC was 7.7%, slightly better than typical healthcare business.

Bio-Techne Trailing 12-Month Return On Invested Capital

We like to invest in businesses with high returns, but the trend in a company’s ROIC is what often surprises the market and moves the stock price. Unfortunately, Bio-Techne’s ROIC has decreased over the last few years. We like what management has done in the past, but its declining returns are perhaps a symptom of fewer profitable growth opportunities.

11. Balance Sheet Assessment

Bio-Techne reported $172.9 million of cash and $350.9 million of debt on its balance sheet in the most recent quarter. As investors in high-quality companies, we primarily focus on two things: 1) that a company’s debt level isn’t too high and 2) that its interest payments are not excessively burdening the business.

Bio-Techne Net Debt Position

With $437.2 million of EBITDA over the last 12 months, we view Bio-Techne’s 0.4× net-debt-to-EBITDA ratio as safe. We also see its $4.54 million of annual interest expenses as appropriate. The company’s profits give it plenty of breathing room, allowing it to continue investing in growth initiatives.

12. Key Takeaways from Bio-Techne’s Q4 Results

It was good to see Bio-Techne narrowly top analysts’ organic revenue expectations this quarter. We were also happy its revenue outperformed Wall Street’s estimates. Overall, we think this was a decent quarter with some key metrics above expectations. The stock remained flat at $64.63 immediately after reporting.

13. Is Now The Time To Buy Bio-Techne?

Updated: February 4, 2026 at 6:37 AM EST

The latest quarterly earnings matters, sure, but we actually think longer-term fundamentals and valuation matter more. Investors should consider all these pieces before deciding whether or not to invest in Bio-Techne.

We see the value of companies making people healthier, but in the case of Bio-Techne, we’re out. Although its revenue growth was decent over the last five years, it’s expected to deteriorate over the next 12 months and its declining operating margin shows the business has become less efficient. And while the company’s strong free cash flow generation allows it to invest in growth initiatives while maintaining an ample cushion, the downside is its subscale operations give it fewer distribution channels than its larger rivals.

Bio-Techne’s P/E ratio based on the next 12 months is 31x. This multiple tells us a lot of good news is priced in - we think there are better opportunities elsewhere.

Wall Street analysts have a consensus one-year price target of $70 on the company (compared to the current share price of $64.63).